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Anthony D. Cristillo, Ph.D.

Patterson LJ, Kuate S, Daltabuit-Test M, Li Q, Xiao P, McKinnon K, DiPasquale J, Cristillo A, Haase A, Robert-Guroff M. Replicating adenovirus-simian immunodeficiency virus (SIV) vectors efficiently prime SIV-specific systemic and mucosal immune responses by targeting myeloid dendritic cells and persisting in rectal macrophages, regardless of immunization route. Clin Vaccine Immunol 19:629-37, 2012.

Cristillo, A.  Increased antibody breadth in lupus rabbits immunized with an envelope-based HIV-1 DNA prime/protein boost vaccine.  International Conference of Clinical and Cellular Immunology.  Chicago, IL.  October 22-24, 2012.

Cristillo AD, Ferrari, MG, Hudacik L, Lewis B, Galmin L, Bowen B, Thompson D, Petrovsky N, Markham P, and Pal R.  Induction of mucosal and systemic antibody and T-cell responses following prime/boost immunization with novel adjuvanted HIV-1 vaccine formulations.  J Gen Virol. 92:128-40, 2011.

Lee, E.M., Chung, H.K., Livesay, J., Suschak, J., Fink, L., Hudacik, L., Galmin, L., Bowen, B., Markham, P., Cristillo, A. and Pal, R. Molecular Methods for Evaluation of Virological Status of Nonhuman Primates Challenged with Simian Immunodeficiency or Simian-Human Immunodeficiency Viruses. J. Virol Methods. 163(2):287-294, 2010

Srinivasan, A., Ayyavoo, V., Mahalingam, S., Kannan, A., Boyd, A., Datta, D., Kalyanaraman, V., Cristillo, A.D., Collman, R., Morellet, N., Sawaya B., and Murali, R. (2008) A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: potential impact on CTL epitopes Virology Journal 5 (1):99.

Cristillo, A.D., Hudacik, L., Restrepo, S., Galmin, L., Suschak, J., Lewis, B., Draghia-Aklib, R., Azizc, N., Weiss, D., Markham P. and Pal, R. (2008) HIV-1 Env Vaccine Comprised of Electroporated DNA and Protein Co-Administered with Talabostat. Biochem Biophys Res Commun 370 (1):22-6.

Cristillo, A.D., Hudacik, L., Restrepo, S., Galmin, L., Suschak, J., Draghia, R., Weiss, D., Markham P. and Pal, R. (2008) Persistent Antibody and T Cell Responses Induced by HIV-1 DNA Vaccine Delivered by Electroporation. Biochem Biophys Res Commun. 366 (1): 29-35.

Barnett, S., Srivastava, I., Kan, E., Pal, R., Cristillo, A.D., Ferrari, M.G., Weiss, D.E and Vajdy, M. (2008) HIV-envelope protein mediated protection against vaginal challenge with SIV/HIV virus following systemic or combined mucosal and systemic immunizations of non-human primates. AIDS 22 (3): 339-48.

Chung, HK., Piese-Masison, C.A., Radonovich, M.F., Brady, J., Lee, J.K., Soo-Young, C., Markham, P., Cristillo, A., and Pal, R.  Celluar Gene Expression Porfiles in Rhesus Macaques Challenged Mucosally with a Pathogenic R5 Tropic simian Human Immunodeficiency Virus Isolate Viral Immunology Dec: 21 (4): 411-423 2008.

Cristillo, A.D., Lisziewicz, J.,  He, L., Hocker, L., Unangst, T., Hudacik, L., Whitney, S., Suschak, J., Camp, K., Trocio, J.N., Whitman, L., Bakare, N., Lori, F., Lu, S., Kalyanaraman, V.S., Markham P. and Pal, R. (2007) HIV-1 Prophylactic Vaccine Comprised of Topical DermaVir Prime and Protein Boost Elicits Cellular Immune Responses and Controls Pathogenic R5 SHIV162P3. Virology 366: 197-211

Peng, B., Voltan, R., Cristillo, A.D., Alvord, W.G., Davis-Warren, A., Zhou, Q., Murthy, K.K. and Robert-Guroff, M. (2006) Replication-competent Ad recombinants encoding non-myristoylated HIV Nef elicit enhanced cellular immunity including Nef-specific CD4+ central memory T cells compared to recombinants encoding wild-type Nef. AIDS  20: 2149-57.

Malkevitch, N.V., Patterson, L.J., Aldrich, M.K., Wu, Y., Venzon, D., Florese, R.H., Kalyanaraman, V.S., Pal, R., Lee, E.M., Zhao, J., Cristillo, A.D. and Robert-Guroff, M. (2006) Durable protection of rhesus macaques immunized with a replicating adenovirus-SIV multigene prime/protein boost vaccine regimen against a second SIVmac251 rectal challenge: role of SIV-specific CD8+ T cell responses. Virology 353: 83-98.

Cristillo, A.D., Wang, S.X., Caskey, M.S., Unangst, T., Hocker, L., He, L., Hudacik, L., Whitney, S., Keen, T., Chou., T-H., Shen, S.Y. , Joshi, S. , Kalyanaraman, V.S. , Nair, B.C., Markham, P. , Lu, S. and Pal, R. (2006) Preclinical Evaluation of Cellular Immune Responses Elicited by a Polyvalent DNA Prime/Protein Boost HIV-1 Vaccine. Virology 346: 151-168.

Pal, R., Wang, S., Kalyanaraman, V.S., Nair, B.C., Whitney, S., Keen, T., Hocker, L., Hudacik, L., Rose, N., Cristillo, A.D., Mboudjeka, I., Shen, S., Wu-Chou, T-H., Montefiori, D., Mascola, J., Lu, S. and Markham, P. (2005) Polyvalent DNA Prime and Envelope Protein Boost HIV-1 Vaccine Elicits Humoral and Cellular Responses and Controls Plasma Viremia in Rhesus Macaques following Rectal challenge with an R5 SHIV Isolate. Journal of Medical Primatology, 34(5-6): 226-236.

Cristillo, A.D., Macri, M.J. and Bierer, B.E. Cloning and characterization of N4WBP5A, an inducible, CsA-sensitive, Nedd4 binding protein in human T lymphocytes. J.Biol.Chem, 2003, 278(36):34587-97.

Cristillo, A.D. and Bierer, B.E. Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin. Mol. Immunol., 2003 40(8):539-53.

Cristillo, A.D., Macri, M.J. and Bierer, B.E. Differential chemokine expression profiles in human peripheral blood T lymphocytes: Dependence on T-cell coreceptor and calcineurin signaling. Blood 101:216-25, 2003.

Cristillo, A.D., Xiao, X., Campbell-Malone, R., Dimitrov, D.S. and Bierer, B.E. Differential HIV viral fusion and CXCR4 cell surface expression in CEM and human peripheral blood T lymphocytes induced by cAMP. Exp. Mol. Pathology 73:9-18, 2002.

Cristillo, A.D., Highbarger, H.C., Dewar, R.L., Dimitrov, D.S., Golding, H. and Bierer, B.E. Up-regulation of HIV-coreceptor CXCR4 expression in human T lymphocytes is mediated, in part, by a cAMP responsive element. FASEB J. 16: 354-364, 2002.

Cristillo, A.D. and Bierer, B.E. Identification of novel targets of immunosuppressive agents by cDNA-based microarray analysis. J. Biol.Chem. 277(6): 4465-4476, 2002.

Li, T.K., Baksh, S., Cristillo, A.D., and Bierer, B.E. Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin. J. Cell. Biochem. 84 (3): 460-471, 2002.

Cristillo, A.D., Mortimer, J.R., Lillicrap, T., and Forsdyke, D.R. Double-Stranded RNA as a Not-Self Alarm Signal: Most Viruses Purine-Load their RNAs, but Some (HTLV-1, Epstein-Barr) Pyrimidine-Load. J. Theoret. Biol. 208 (4): 475-491, 2001.

Cristillo A.D. and Bierer B.E. Immunophilins and the immunophilin binding agents.  In: Rich, ed.  Clinical Immunology, 2nd edition. London: Harcourt Health Sciences, 2001.

Cristillo A.D. and Bierer B.E. (2001)  Calcineurin as a therapeutic target.  In: Austen, Frank, Atkinson, Cantor, eds.  Samter's Immunologic Diseases, 6th edition.  Baltimore: Lippincott Williams & Wilkins.

Heximer, S.P., Cristillo, A.D., Russell, L. and Forsdyke, D.R. Expression and processing of G0/G1 switch gene 24 (G0S24/TIS11/TTP/NUP475) RNA in cultured human blood mononuclear cells. DNA Cell Biol.17: 249-263, 1998.

Cristillo, A.D., Heximer, S.P., Russell, L., and Forsdyke, D.R. Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) in cultured human blood mononuclear cells. DNA Cell Biol.16: 1449-1458, 1997.

Heximer, S.P., Cristillo, A.D. and Forsdyke, D.R. Comparison of mRNA expression of two regulators of G-protein signaling, RGS1/BL34/1R20 and RGS2/G0S8, in human blood mononuclear cells. DNA Cell Biol. 16: 589-598, 1997.

Cristillo, A.D., Heximer, S.P. and Forsdyke, D.R. A "stealth" approach to inhibition of lymphocyte activation by oligonucleotides complementary to the putative G0/G1 switch regulatory gene GOS30/EGR1/NGFI-A. DNA Cell Biol.15: 561-570, 1996.

Heximer, S.P., Cristillo, A.D., Russell, L., and Forsdyke, D.R. Sequence analysis and expression in cultured lymphocytes of the human FOSB gene (G0S3). DNA Cell Biol. 15: 1025-1038, 1996.

 

 

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