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Efficacy and Potency Testing:
Molecular Assays

ABL has decades of experience working with human and animal samples to determine the efficacy, activity, and potency of vaccines and therapeutics. Our animal facility is located in close proximity to our laboratories allowing for fresh samples to be delivered in a timely manner for testing in ABL's laboratories.  ABL has a wealth of experience processing many different types of samples (blood, fluids, tissues, washes, etc) and viably freezing cells for shipment or testing at a later date.

In our continuing effort to ensure we are providing our clients with reliable and consistent data, ABL has worked with some of the top academic labs and experts in the county to cross validate our assays and sample collection techniques. This helps give our clients the assurance that the information they receive from ABL is accurate and can be used to make the significant decisions about their product candidates.

Our goal in providing a wide range of testing capabilities is to ensure the data accuracy to help our clients remove the risk associated with product development.

Capabilities:

  • Detection of proviral DNA by real time PCR
  • Detection of viral load by NASBA
  • Detection of viral vectors (adenovirus, MVA, AAV, etc) by quantitative PCR and RT-PCR
  • Detection of cytokines and other biomarker responses
  • Detection of host restriction factors
  • Examination of virus-host interactions and global gene expression profiles to help understand molecular mechanisms of immune correlation of protection
    • Haplotyping for NHP’s
    • Trim 5a testing
    • Virus load determination

Please contact ABL to speak with our scientists about your immunogenicity study program.

ABL, Inc.
9800 Medical Center Drive
Building D
Rockville, MD, 20850

Toll Free: 800-225-5600
Local: 301-881-5600
Fax: 301-816-5438

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For information about Catalog Products, please call: 301-816-5200 or email