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Efficacy and Potency Testing:
Cellular Immunity

ABL has decades of experience working with human and animal samples to determine the efficacy, activity, and potency of vaccines and therapeutics. Our animal facility is located in close proximity to our laboratories allowing for fresh samples to be delivered in a timely manner for testing in ABL's laboratories.  ABL has a wealth of experience processing many different types of samples (blood, fluids, tissues, washes, etc) and viably freezing cells for shipment or testing at a later date.

In our continuing effort to ensure we are providing our clients with reliable and consistent data, ABL has worked with some of the top academic labs and experts in the county to cross validate our assays and sample collection techniques. This helps give our clients the assurance that the information they receive from ABL is accurate and can be used to make the significant decisions about their product candidates.

Our goal in providing a wide range of testing capabilities is to ensure the data accuracy to help our clients remove the risk associated with product development.

Capabilities:

• Determining absolute values and percentages of CD4 T-cells, CD8 T-cells, B cells, and NK cells from whole blood samples
• Examine memory T-cell responses by FACS
• NK functionality
• Quatify secreted cytokines
• ELISPOT – mouse and rhesus samples
• Intracellular cytokine staining
• Luminex 
• FACS analysis to quantitate or determine production of IFN-gamma, TNF-alpha, IL-2, IL-4, IL-5, IL-6, IL-10, and other cytokines
• Flex array system to target other cytokines/chemokines Cytometric bead array
• Lymphoproliferation assay

Please contact ABL to speak with our scientists about your immunogenicity study program.

ABL, Inc.
9800 Medical Center Drive
Building D
Rockville, MD, 20850

Toll Free: 800-225-5600
Local: 301-881-5600
Fax: 301-816-5438

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For information about Catalog Products, please call: 301-816-5200 or email